EN
TÜRKÇE
Poster - 28
Quality of life at the age of 6 years in children operated at birth for esophageal atresia
E Bitoumbou*, A Bonnard**, A Lapillonne***, C Jacquier****, M Antoine*****, N Caron******, A Guinot*******, T Lamireau********, S Irtan*********, L Bridoux-Henno**********, C Dumant***********, A Breton************, J Lirussi Borgnon*************, I Talon**************, A Fabre***************, N Panait***************, A Ranke****************, F Laconi*****************, V Fouquet******************, N Kalfa*******************, D Djeddi********************, S Willot*********************, C Dupont**********************, A Turquet***********************, C Crémillieux************************, E Darviot*************************, C Borderon**************************, O Jaby***************************, M Pouzac****************************, C Pelatan*****************************, A Comte******************************, P De Vries*******************************, A Nicolas********************************, V Triolo*********************************, C Tölg**********************************, S Geiss***********************************, L Cadart*****, F Gottrand*****, M Aumar*****
*Lille University Hospital, Lille, France
**University Hospital of APHP Robert Debré, Paris, France
***University Hospital of APHP Necker-Enfants Malades, Paris, France
****University Hospital of Grenoble Alpes, Grenoble, France
*****Lille University Hospital, Lille, France
******University Hospital of HCL Lyon, Lyon, France
*******University Hospital of Nantes, Nantes, France
********University Hospital of Bordeaux, Bordeaux, France
*********University Hospital of APHP Armand Trousseau, Paris, France
**********University Hospital of Rennes, Rennes, France
***********University Hospital of Rouen, Rouen, France
************University Hospital of Toulouse, Toulouse, France
*************University Hospital of Dijon, Dijon, France
**************University Hospital of Strasbourg, Strasbourg, France
***************AP-HM University Hospital Centre Marseille
****************University Hospital of Nancy, Nancy, France
*****************University Hospital of Reims, Reims, France
******************AP-HP Bicêtre Hospital
*******************University Hospital of Montpellier, Montpellier, France
********************University Hospital of Amiens, Amiens, France
*********************University Hospital of Tours, Tours, France
**********************University Hospital of Caen, Caen, France
***********************University Hospital of La Réunion, Saint Denis de la Réunion, France
************************University Hospital of Saint-Etienne, Saint-Etienne, France
*************************University Hospital of Angers, Angers, France
**************************University Hospital of Clermont-Ferrand, Clermont-Ferrand, France
***************************Hospital of Créteil, Créteil, France
****************************University Hospital of Orléans, Orléans, France
*****************************Hospital of Le Mans, Le Mans, France
******************************University Hospital of Besançon, Besançon, France
*******************************University Hospital of Brest, Brest, France
********************************University Hospital of Limoges, Limoges, France
*********************************University Hospital of Nice, Nice, France
**********************************University Hospital of Fort De France, Martinique, France
***********************************Hospital of Colmar, Colmar, France
Since esophageal atresia (EA) is a lifelong chronic condition, it may impact on the daily life. This study aimed to assess the quality of life (QoL) at age 6 years in children with EA as reported by children and their parents. Secondary objectives were to evaluate the concordance between child and parent responses, compare QoL in children with pure EA versus other EA types, and identify predictors of impaired QoL.
This prospective, population-based nested-cohort study included data at 6 years of children born between 2010 and 2012 within our national EA registry. QoL was prospectively assessed for both parents and children using the generic PedsQL 4.0 scale.
A total of 230 children were included. At age 6, the median overall QoL score assessed by children was 80/100 (IQR: 69.7–89.2) while the median parental score was 78.4/100 (IQR: 65.0–88.3), with a moderate but significant concordance (intraclass correlation coefficient: 0.47, p<0.05). QoL in children with pure EA was not significantly different from that of other EA types (p=0.52 for children, p=0.75 for parents). Long-term respiratory treatment at age 1 was the only factor significantly associated with impaired QoL (p=0.045). At age 6, respiratory symptoms and at least one respiratory exacerbation in the preceding year were strongly associated with poorer QoL in children (p=0.007 and p=0.017, respectively). Parental assessments further identified respiratory symptoms, exacerbations and orthopedic abnormalities as significant predictors of impaired QoL (p=0.001, p=0.009, and p=0.026, respectively).
Our findings reveal a good overall QoL at age 6 in children with EA, highlighting the effectiveness of adaptive coping strategies developed in the context of a chronic condition from birth. However, respiratory and orthopedic complications remain critical factors influencing QoL and warrant targeted interventions.